Probiotic effectiveness is strain-specific, not species-generic. A product listing "Lactobacillus" or "Bifidobacterium" on its label without a full strain designation offers no reliable prediction of benefit. For gut flora health, look for strains that are individually named, clinically studied in combination, and backed by peer-reviewed publications. Bio-K+'s three proprietary strains — Lacticaseibacillus casei LBC80R®, Lacticaseibacillus rhamnosus CLR2®, and Lactobacillus acidophilus CL1285® — are patented and have been studied together, not in isolation, across 45+ peer-reviewed publications and 16 published clinical trials. This is the standard Bio-K+ holds itself to, and the reason we guarantee our CFU count until the expiration date when stored at room temperature.